Welcome to LookChem.com Sign In|Join Free
  • or
1,2-Ethanediamine,N1,N1-bis(2-chloroethyl)-N2-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride(1:2), also known as AMSA hydrochloride, is a synthetic antineoplastic agent primarily used as an anti-cancer medication. It is a hydrochloride salt form of the compound that functions by inhibiting the activity of topoisomerase II, an enzyme crucial for DNA replication and repair. This inhibition results in the death of cancer cells, making it a potent agent in the fight against various types of cancer.

10072-25-0

Post Buying Request

10072-25-0 Suppliers

Recommended suppliers

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

10072-25-0 Usage

Uses

Used in Oncology:
1,2-Ethanediamine,N1,N1-bis(2-chloroethyl)-N2-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride(1:2) is used as an anti-cancer agent for the treatment of various types of cancer, including leukemia, lymphoma, and solid tumors. Its mechanism of action involves the inhibition of topoisomerase II, leading to the disruption of DNA replication and repair, and ultimately causing the death of cancer cells.
However, due to its severe side effects, such as myelosuppression, cardiac toxicity, and the potential for secondary malignancies, the use of 1,2-Ethanediamine,N1,N1-bis(2-chloroethyl)-N2-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride(1:2) is closely monitored and regulated by healthcare professionals in a clinical setting. This ensures that the benefits of the medication are maximized while minimizing the risks associated with its use.

Check Digit Verification of cas no

The CAS Registry Mumber 10072-25-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,0,7 and 2 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10072-25:
(7*1)+(6*0)+(5*0)+(4*7)+(3*2)+(2*2)+(1*5)=50
50 % 10 = 0
So 10072-25-0 is a valid CAS Registry Number.

10072-25-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1,2-Ethanediamine,N1,N1-bis(2-chloroethyl)-N2-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride(1:2)

1.2 Other means of identification

Product number -
Other names N,N-bis-(2-chloro-ethyl)-N'-(6-chloro-2-methoxy-acridin-9-yl)-ethylenediamine,dihydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10072-25-0 SDS

10072-25-0Downstream Products

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1 Customer Service

What can I do for you?
Get Best Price

Get Best Price for 10072-25-0