10073-86-6Relevant academic research and scientific papers
Reaction of Dimethyl- and Diethylmalonyl Dichlorides with Aromatic Amides
Yakovlev,Zakhs,Prep'yalov,Rebrov
, p. 650 - 652 (2007/10/03)
Dimethylmalonyl dichloride reacts with substituted benzamides with formation of mixtures of 2-aryl-5,5-dimethyl-1,3-oxazine-4,6-diones and N,N'-bis(aroyl)dimethylmalonediamides whose ratio depends on the reactant concentration. Under similar conditions, diethylmalonyl dichloride with the same amides gives only N,N'-bis(aroyl)diethylmalonediamides.
AZOLES AND AZINES. 62. STRUCTURE OF 2-ARYL-1,3-OXAZINE-4,6-DIONES
Zakhs, V. E.,Yakovlev, I. P.,Smorygo, N. A.,Gindin, V. A.,Ivin, B. A.
, p. 325 - 332 (2007/10/02)
1H, 13C NMR, IR, and UV spectra have been studied for solutions of a number of potentially tautomeric 2-aryl-1,3-oxazine-4,6-diones and their 5-methyl substituted analogs with variation of substitutent at the para position of the benzene ring, as well as compounds with a fixed structure that simulates possible tautomeric forms.The data have been compared with the results of quantum chemical calculations carried out in SSO MO LCAO approximation by the CNO, CNDO/2, and MPNDO/3 methods.In DMSO and THF solution the test compounds exist predominantly as 2-aryl-4-hydroxy-6H-1,3-oxazin-6-ones.The para substituent in the benzene ring does not effect the composition of the tautomer mixture significantly.
