1007568-25-3Relevant academic research and scientific papers
Discovery of highly potent small molecule Hepatitis C Virus entry inhibitors
Mittapalli, Gopi Kumar,Jackson, Andrew,Zhao, Fang,Lee, Haekyung,Chow, Stephine,McKelvy, Jeffrey,Wong-Staal, Flossie,MacDonald, James E.
, p. 6852 - 6855 (2011)
Novel, highly potent small molecule HCV entry inhibitors are reported. The SAR exploration of a hit molecule identified from screening of a compound library led to the identification of highly potent compounds with IC 50 values of 5 nM in the tissue culture HCV infectious assay.
HEPATITIS C VIRUS ENTRY INHIBITORS
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Page/Page column 90, (2010/11/30)
The present invention relates to the use of tricyclic diphenylamine derivative compounds for prevention and/or treatment of Hepatitis C virus (HCV) infection by inhibiting HCV entry into permissive cells.
