1007571-63-2

Upstream product

• 6575-00-4 3,5-dichlorobenzonitrile 
• 473923-96-5 3-chloro-5-methoxybenzonitrile 
• 473923-97-6 3-chloro-5-hydroxybenzonitrile 
• 1007571-62-1 3-chloro-5-(3,6-dibromo-2-fluoro-phenoxy)-benzonitrile 
• 1068-55-9 isopropylmagnesium chloride 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1007571-64-3 3-(6-bromo-2-fluoro-3-hydroxymethyl-phenoxy)-5-chloro-benzonitrile 
• 1089178-84-6 C₂₃H₁₇BrClFN₂O₃ 
• 1095279-71-2 C₂₀H₁₇BrClFN₂O₃ 
• 1007571-61-0 3-(6-bromo-3-(bromomethyl)-2-fluorophenoxy)-5-chlorobenzonitrile 
• 1089178-99-3 C₁₈H₁₅BrClFN₂O₃ 
• 1089178-54-0 3-[3-(4-amino-2-oxo-2H-pyrimidin-1-ylmethyl)-6-bromo-2-fluoro-phenoxy]-5-chloro-benzonitrile 
• 1089178-58-4 3-[6-bromo-3-(2,4-dioxo-imidazolidin-1-ylmethyl)-2-fluoro-phenoxy]-5-chloro-benzonitrile 
• 1089178-48-2 3-[6-bromo-3-(2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethyl)-2-fluoro-phenoxy]-5-chloro-benzonitrile 
• 1089178-61-9 3-[6-bromo-2-fluoro-3-(3-methyl-2,5-dioxo-imidazolidin-4-ylmethyl)-phenoxy]-5-chloro-benzonitrile 
• 1089179-02-1 C₁₈H₁₀BrClFN₃O₂S 
• 1089179-03-2 C₁₈H₁₀BrClFN₃O₃ 
• 1089178-62-0 C₁₉H₁₂BrClFN₃O₃ 
• 1089178-98-2 C₂₃H₂₃BrClFN₂O₅ 
• 1089179-00-9 C₂₃H₂₂BrClFNO₅ 

Relevant academic research and scientific papers

Non-Nucleoside reverse transcriptase inhibitors

Compounds of formula I, wherein R1, R2, R3, X and Ar, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS

Compounds of formula (I), wherein R1, X1, X2 and A, are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula (I) useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

Non-nucleoside reverse transcriptase inhibitors

Compounds of formula I, wherein R1, R2, R3, R4, Ra, X, X1, and Y are as defined herein or pharmaceutically acceptable salts thereof, inhibit HIV-1 reverse transcriptase and afford a method for prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC. The present invention also relates to compositions containing compounds of formula I useful for the prevention and treatment of HIV-1 infections and the treatment of AIDS and/or ARC.

Non-nucleoside reverse transcriptase inhibitors

The present invention provides for compounds useful for treating an HIV infection, or preventing an HIV infection, or treating AIDS or ARC. The compounds of the invention are of formula I wherein A is A1, A2, A3 or A4 and R1, R2, R3, R4a, R4b, R5, R6, Ar, X1, X2, X4, X4 and X5 are as herein defined. Also disclosed in the present invention are methods of treating an HIV infection with compounds defined herein and pharmaceutical compositions containing said compounds.