1007597-75-2

Upstream product

• 629-05-0 n-octyne 
• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 38761-67-0 1-bromo-1-octyne 

Downstream Products

• 1116153-78-6 N-methyl-N-[(Z)-2-(phenylsulfanyl)-1-octenyl]-p-toluenesulfonamide 
• 1433278-66-0 2-((1,3-dithian-2-ylidene)methyl)-N-methyl-N-tosyloctanamide 
• 1486515-50-7 (E)-N-methyl-N-(1-tributylstannyl-oct-1-en-1-yl)tosylamide 
• 1486515-82-5 N,N'-[(1Z,4Z)-1-cyclopropyl-3-oxoundeca-1,4-diene-2,4-diyl]bis(N-methyltosylamide) 
• 1486515-81-4 N,N'-((7Z,10Z)-9-oxoheptadeca-7,10-diene-8,10-diyl)bis(N,4-dimethylbenzenesulfonamide) 
• 1486515-68-7 methyl (Z)-2-(N-methyltosylamido)non-2-enoate 
• 1486515-66-5 dimethyl 4-(N-methyltosylamido)-3-hexylcyclohexa-1,4-diene-1,2-dicarboxylate 
• 1486515-64-3 (Z)-N-(1-phenyloct-1-en-1-yl)-N-methyltosylamide 
• 1486515-63-2 (Z)-N,4-dimethyl-N-(1-phenyloct-1-en-1-yl)benzenesulfonamide 
• 1486515-62-1 (Z)-N-(1-phenyldec-3-en-1-yn-3-yl)-N-methyltosylamide 
• 1486515-60-9 (Z)-N-(1-phenyl-non-2-en-2-yl)-N-methyltosylamide 
• 1486515-59-6 (Z)-N-[1-(4-nitrophenyl)oct-1-en-1-yl]-N-methyltosylamide 
• 1486515-58-5 (E)-N-(1-fluorooct-1-en-1-yl)-N-methyltosylamide 

Relevant academic research and scientific papers

Copper-catalyzed extended pummerer reactions of ketene dithioacetal monoxides with alkynyl sulfides and ynamides with an accompanying oxygen rearrangement

The first examples of metal-catalyzed extended Pummerer reactions through the activation of sulfoxides are described. The copper-catalyzed reactions of ketene dithioacetal monoxides with alkynyl sulfides and ynamides provided a wide variety of γ,γ-disulfanyl-β,γ-unsaturated carbonyl compounds with an accompanying oxygen rearrangement. The products can be easily converted into 1,4-dicarbonyl compounds and substituted heteroaromatics. DFT calculations and mechanistic experiments revealed a new interesting stepwise addition/oxygen rearrangement mechanism. Beyond Pummerer: The first examples of copper-catalyzed extended Pummerer reactions of ketene dithioacetal monoxides with alkynyl sulfides and ynamides provided a wide variety of γ,γ-disulfanyl-β,γ-unsaturated carbonyl compounds with an accompanying oxygen rearrangement (see scheme). The products can be easily converted into 1,4-dicarbonyl compounds and substituted heteroaromatics. DFT calculations and mechanistic experiments revealed a new interesting stepwise addition/oxygen-rearrangement mechanism.

Syntheses of α-stannylated and α-iodinated enamides via molybdenum-catalyzed hydrostannation

α-Stannylated and α-iodinated enamides can easily be obtained by molybdenum-catalyzed regio- and stereoselective hydrostannation and subsequent tin-iodine exchange. These functionalized enamides are interesting building blocks for a wide range of cross-coupling reactions giving access to various types of α-substituted enamides.

Radical additions of arenethiols to ynamides for the selective synthesis of N-[(Z)-2-(Arylsulfanyl)-1-alkenyl]amides

A variety of ynamides undergo highly regio- and stereoselective radical addition of arenethiols with the aid of trie- thylborane as a radical initiator. The products, N-[-2-arylsulfanyl-1 -alkenyl]amides, can be reduced with triethyl- silane in trifluoroa

Copper-catalyzed aerobic oxidative amidation of terminal alkynes: Efficient synthesis of ynamides

A copper-catalyzed method for the preparation of ynamides has been identified that proceeds via aerobic oxidative coupling of terminal alkynes with various nitrogen nucleophiles, including cyclic carbamates, amides and ureas, and N-alkyl-arylsulfonamides and indoles. Copyright