1486515-63-2

Upstream product

• 873-51-8 phenylborondichloride 
• 640-61-9 N-methyl-p-toluenesulfonylamide 
• 629-05-0 n-octyne 
• 1486515-54-1 (E)-N-(1-iodooct-1-en-1-yl)-N-methyltosylamide 
• 98-80-6 phenylboronic acid 
• 1007597-75-2 N,4-dimethyl-N-(oct-1-yn-1-yl)benzenesulfonamide 
• 1486515-50-7 (E)-N-methyl-N-(1-tributylstannyl-oct-1-en-1-yl)tosylamide 

Relevant academic research and scientific papers

Regio- and Stereoselective 1,2-Carboboration of Ynamides with Aryldichloroboranes

Catalyst-free 1,2-carboboration of ynamides is presented. Readily available aryldichloroboranes react with alkyl- or aryl-substituted ynamides in high yields with complete regio- and stereoselectivity to valuable β-boryl-β-alkyl/aryl α-aryl substituted enamides which belong to the class of trisubstituted alkenylboronates. The 1,2-carboboration reaction is experimentally easy to conduct, shows high functional group tolerance and broad substrate scope. Gram-scale reactions and diverse synthetic transformations convincingly demonstrate the synthetic potential of this method. The reaction can also be used to access 1-boraphenalenes, a class of boron-doped polycyclic aromatic hydrocarbons.

Syntheses of α-stannylated and α-iodinated enamides via molybdenum-catalyzed hydrostannation

α-Stannylated and α-iodinated enamides can easily be obtained by molybdenum-catalyzed regio- and stereoselective hydrostannation and subsequent tin-iodine exchange. These functionalized enamides are interesting building blocks for a wide range of cross-coupling reactions giving access to various types of α-substituted enamides.