100764-07-6Relevant academic research and scientific papers
Directed regio- and stereoselective hydroformylation of mono- and 1,3-disubstituted allylic alcohols: A catalytic approach to the anti-aldol-retron
Breit, Bernhard,Demel, Peter,Gebert, Antje
, p. 114 - 115 (2004)
Regioselective and diastereoselective hydroformylation of mono- and 1,3-disubstituted allylic alcohol o-DPPB esters is described. The products represent synthetically important anti-aldol retrons.
Tandem-directed regioselective hydroformylation/β-elimination: A practical method for the synthesis of enals
Bruch, Achim,Gebert, Antje,Breit, Bernhard
experimental part, p. 2169 - 2176 (2009/04/10)
A practical synthesis of α,β-unsaturated aldehydes by a tandem-directed hydroformylation/β-elimination process of allylic o-DPPB esters is reported. The o-DPPB group served as an effective controller for regioselectivity of the hydroformylation towards th
Oxopropenylation of Alkylmagnesium Halides by 3-(Trimethylsilyloxy)acroleins
Ullrich, Friedrich-Wilhelm,Rotscheidt, Klaus,Breitmaier, Eberhard
, p. 1737 - 1744 (2007/10/02)
Oxopropenylation of alkylmagnesium halides 4 by 3-(trimethylsilyloxy)acroleins 3 selectively yields the (E)-isomers of α,β-unsaturated aldehydes such as 4-phenyl-2-butenals 9, 3-cyclopropylpropenals 10, 3-cyclohexylpropenals 11, 3-(3-menthyl)propenals 12, and 2,5-hexadienals 13. 3-Hydroxyenolsilylethers 6 are isolated when allylmagnesium chloride is used as carbon nucleophile; to conclude, the reaction primarily involves nucleophilic addition of the Grignard reagent at the aldehyde carbon of the acrolein 3.
