1007797-89-8Relevant articles and documents
Identification of diarylsulfonamides as agonists of the free fatty acid receptor 4 (FFA4/GPR120)
Sparks, Steven M.,Chen, Grace,Collins, Jon L.,Danger, Dana,Dock, Steven T.,Jayawickreme, Channa,Jenkinson, Stephen,Laudeman, Christopher,Leesnitzer, M. Anthony,Liang, Xi,Maloney, Patrick,McCoy, David C.,Moncol, David,Rash, Vincent,Rimele, Thomas,Vulimiri, Padmaja,Way, James M.,Ross, Sean
, p. 3100 - 3103 (2014/06/24)
The exploration of a diarylsulfonamide series of free fatty acid receptor 4 (FFA4/GPR120) agonists is described. This work led to the identification of selective FFA4 agonist 8 (GSK137647A) and selective FFA4 antagonist 39. The in vitro profile of compounds 8 and 39 is presented herein.