321309-38-0

Usage

Uses

Used in Pharmaceutical Industry:
3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonyl chloride is used as a synthetic intermediate for the introduction of sulfonyl groups into pharmaceutical molecules. The sulfonyl group can confer beneficial pharmacological properties to these molecules, enhancing their therapeutic potential.
Used in Agrochemical Synthesis:
In the agrochemical industry, 3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonyl chloride is utilized as a key component in the synthesis of various agrochemicals. Its ability to introduce sulfonyl groups can improve the efficacy and selectivity of these compounds in agricultural applications.
Used in Organic Synthesis:
3,4-Dihydro-2H-1,5-benzodioxepine-7-sulfonyl chloride is used as a reagent in a variety of chemical reactions, including sulfonylation and other organic transformations. Its reactivity makes it a valuable tool for the preparation of a wide range of organic compounds, contributing to the development of new materials and chemical entities.

InChI:InChI=1/C9H9ClO4S/c10-15(11,12)7-2-3-8-9(6-7)14-5-1-4-13-8/h2-3,6H,1,4-5H2

Upstream product

• 7216-18-4 3,4-dihydro-2H-benzo[b][1,4]dioxepine 

Downstream Products

• 1402597-53-8 N-((R)-1-benzofuran-2-yl(phenyl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1007797-89-8 C₁₈H₂₁NO₄S 
• 1402598-88-2 N-((R)-(2-chlorophenyl)(7-(4-((1S)-2,2,2-trifluoro-1-hydroxy-1-methylethyl)-2-pyridinyl)-1-benzothiophen-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1402598-84-8 N-((R)-(2-chlorophenyl)(7-(4-((1R)-2,2,2-trifluoro-1-hydroxy-1-methylethyl)-2-pyridinyl)-1-benzothiophen-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1402607-92-4 N-((R)-(2-chlorophenyl)(7-(4-(2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl)-2-pyridinyl)-1-benzothiophen-2-yl)methyl)-3,4-dihydro-2H-1,5-benzodioxepine-7-sulfonamide 
• 1203493-77-9 1-(2,6-difluorophenylsulfonyl)-4-(3,4-dihydro-2H-benzo[b][1,4]dioxepin-7-ylsulfonyl)piperazine 
• 956467-59-7 N-{2-[{[3,4-bis(methyloxy)phenyl]sulfonyl}(methyl)amino]ethyl}-N-methyl-3,4-dihydro-2H-1,5-benzodioxepin-7-sulfonamide 

Relevant academic research and scientific papers

Multicyclic sulfonamide compounds as inhibitors of histone deacetylase for the treatment of disease

Disclosed herein are sulfonamide compounds of Formula VII as described herein. Methods and compositions are disclosed for treating disease states including, but not limited to cancers, autoimmune diseases, tissue damage, central nervous system disorders, neurodegenerative disorders, fibrosis, bone disorders, polyglutamine-repeat disorders, anemias, thalassemias, inflammatory conditions, cardiovascular conditions, and disorders in which angiogenesis play a role in pathogenesis, using the compounds of the invention. In addition, methods of modulating the activity of histone deacetylase (HDAC) are also disclosed.