1007834-20-9Relevant academic research and scientific papers
Improved Syntheses of Benzyl Hydraphile Synthetic Cation-Conducting Channels
Curvey, Nichole S.,Luderer, Sarah E.,Walker, John K.,Gokel, George W.
, p. 2771 - 2779 (2014)
The tris(macrocycle)s that function in bilayer membranes as ion channels have recently shown versatile new applications such as antibiotic synergists and as agents for direct injection chemotherapy. This report records the development of new and versatile approaches to these molecules that produce significantly better overall yields for a group of previously reported hydraphiles having spacer chains ranging from octylene to hexadecylene.
Heterocyclic amide hydraphile synthetic cation transporters
Wang, Wei,Yamnitz, Carl R.,Gokel, George W.
experimental part, p. 825 - 839 (2009/09/08)
A family of hydraphile ionophores has been prepared in which various ～CH2N～ to ～CON～ replacements have been made to assess the effect on Na+ transport through phospholipid bilayers. When the central relay (see graphical abstract) was
