1007871-99-9Relevant academic research and scientific papers
Sulfuric acid mediated heterocyclization of Ortho-cyanomethylnitroarenes to benzo[C]isoxazoles and fused benzo[C]isoxazoles
Bakavoli, Mehdi,Pordel, Mehdi,Rahimizadeh, Mohammad,Jahandari, Pooneh,Seresht, Esmaeel Rezaei
, p. 165 - 171 (2008/09/20)
The vicarious nucleophilic substitution of hydrogen (VNS) is used as the key step to convert substituted 5-nitrobenzimidazoles 1a-b into their ortho-cyanomethyl derivatives 2a-b. Conc. sulfuric acid mediated heterocyclization of these intermediates gave t
