100795-92-4 Usage
General Description
(5E)-3-(2-aminoethyl)-5-(4-methoxybenzylidene)-1,3-thiazolidine-2,4-dione hydrochloride is a chemical compound with potential pharmacological properties. It is a thiazolidinedione derivative, which is a class of compounds known for their antidiabetic and anti-inflammatory effects. This specific compound contains an amine group, a methoxybenzylidene group, and a thiazolidinedione ring, all contributing to its potential biological activity. The hydrochloride salt form of the compound suggests that it may be more stable and soluble in water, making it easier to use in pharmaceutical formulations. More research is needed to fully understand the potential therapeutic uses and mechanisms of action of this compound.
Check Digit Verification of cas no
The CAS Registry Mumber 100795-92-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,7,9 and 5 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 100795-92:
(8*1)+(7*0)+(6*0)+(5*7)+(4*9)+(3*5)+(2*9)+(1*2)=114
114 % 10 = 4
So 100795-92-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H14N2O3S/c1-18-10-4-2-9(3-5-10)8-11-12(16)15(7-6-14)13(17)19-11/h2-5,8H,6-7,14H2,1H3/b11-8+
100795-92-4Relevant articles and documents
Structure-activity relationship (SAR) studies of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione: Development of potential substrate-specific ERK1/2 inhibitors
Li, Qianbin,Al-Ayoubi, Adnan,Guo, Tailiang,Zheng, Hui,Sarkar, Aurijit,Nguyen, Tri,Eblen, Scott T.,Grant, Steven,Kellogg, Glen E.,Zhang, Shijun
scheme or table, p. 6042 - 6046 (2010/05/18)
A series of analogs of 3-(2-amino-ethyl)-5-(4-ethoxy-benzylidene)-thiazolidine-2,4-dione, a putative substrate-specific ERK1/2 inhibitor, were synthesized and biologically characterized in human leukemia U937 cells to define its pharmacophore. It was disc