100796-66-5Relevant articles and documents
Synthesis and in vitro antimicrobial study of 4-thiazolidinone containing sulfanilamide
Zevzikoviene, Augusta,Zevzikovas, Andrejus,Tarasevicius, Eduardas,Pavlonis, Alvydas,Dirse, Vidmantas
, p. 911 - 915 (2012/10/29)
The title compounds, 3-allyl-2-sulfanylamido-4-thiazolidinones (2a-d), have been synthesized after substitution of amino group of sulfanylamide with allylisothiocyanate and cyclization into 4-thiazolidinones. The synthesized compounds were tested for their antibacterial and antifungal activity (MIC) in vitro against microorganisms: S. aureus, E. faecalis, E. coli, P. aeruginosa, K. pneumoniae, P. mirabilis, B. subtilis, B. cereus and C. albicans taking sulfadimidine, sulfathiazole, sulfanilamide and sulfamethizole as standard drugs. Synthesized compounds (2a-d) demonstrated selective activity against B. cereus.