1008109-24-7

Basic information

• Product Name: C₂₁H₁₇ClN₂O₂
• Synonyms: C₂₁H₁₇ClN₂O₂
• CAS NO: 1008109-24-7
• Molecular Weight: 364.831
• Mol File: 1008109-24-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₁H₁₇ClN₂O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₁₇ClN₂O₂(1008109-24-7)
• EPA Substance Registry System: C₂₁H₁₇ClN₂O₂(1008109-24-7)

Safety Data

• Hazardous Substances Data: 1008109-24-7(Hazardous Substances Data)

Upstream product

• 824-94-2 p-methoxybenzyl chloride 
• 50892-62-1 8-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one 

Relevant articles and documents

USE OF N-DESMETHYLCLOZAPINE AND RELATED COMPOUNDS AS DOPAMINE STABILIZING AGENTS

Disclosed herein is the use of N-desmethylclozapine (NDMC) and related compounds to treat a variety of neuropsychiatric diseases including psychosis. It is shown that NDMC and related compounds are agonists or partial agonists at D2 and D3 dopamine receptors and thus may be effective as a dopamine stabilizing agent, allowing it to be used to treat or provide reduced incidence of Extrapyramidal symptoms (EPS) and/or tardive dyskinesias (TD). Also disclosed is administering NDMC and related compounds in combination with other anti-psychotic agents.