100824-06-4Relevant academic research and scientific papers
Development of tubulin-polymerization inhibitors based on the thalidomide skeleton
Aoyama, Hiroshi,Noguchi, Tomomi,Misawa, Takashi,Nakamura, Takanori,Miyachi, Hiroyuki,Hashimoto, Yuichi,Kobayashi, Hisayoshi
, p. 944 - 949 (2007)
We synthesized a series of compounds based on the potent tubulin-polymerization inhibitor 5-hydroxy-2-(2,6-diisopropylphenyl)-1H- isoindole-1,3-dione [5HPP-33 (3)], which is structurally derived from thalidomide (1), and investigated their inhibitory effe
