100856-78-8

Basic information

• Product Name: N-(3,4,5-trimethoxyphenylcarbamothioyl)benzamide
• Synonyms: N-(3,4,5-trimethoxyphenylcarbamothioyl)benzamide
• CAS NO: 100856-78-8
• Molecular Weight: 346.407
• Mol File: 100856-78-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(3,4,5-trimethoxyphenylcarbamothioyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4,5-trimethoxyphenylcarbamothioyl)benzamide(100856-78-8)
• EPA Substance Registry System: N-(3,4,5-trimethoxyphenylcarbamothioyl)benzamide(100856-78-8)

Safety Data

• Hazardous Substances Data: 100856-78-8(Hazardous Substances Data)

Upstream product

• 532-55-8 Benzoyl isothiocyanate 
• 24313-88-0 3,4,5-Trimethoxyaniline 
• 98-88-4 benzoyl chloride 

Downstream Products

• 59083-54-4 1-(3,4,5-trimethoxyphenyl)thiourea 
• 100856-59-5 N-(5,6,7-Trimethoxy-benzothiazol-2-yl)-benzamide 

Relevant articles and documents

Synergism of fused bicyclic 2-aminothiazolyl compounds with polymyxin B against: Klebsiella pneumoniae

A series of fused bicyclic 2-aminothiazolyl compounds were synthesized and evaluated for their synergistic effects with polymyxin B (PB) against Klebsiella pneumoniae (SIPI-KPN-1712). Some of the synthesized compounds exhibited synergistic activity. When 4 μg ml-1 compound B1 was combined with PB, it showed potent antibacterial activity, achieving 64-fold reduction of the MIC of PB. Furthermore, compound B1 showed prominent synergistic efficacy in both concentration gradient and time-kill curves in vitro. In addition, B1 combined with PB also exhibited synergistic and partial synergistic effect against E. coli (ATCC25922 and its clinical isolates), Acinetobacter baumannii (ATCC19606 and its clinical isolates), and Pseudomonas aeruginosa (Pae-1399).