Cas 100866-82-8,methyl 3-acetyl-2-methylquinoline-4-carboxylate

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Check Digit Verification of cas no

The CAS Registry Mumber 100866-82-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,8,6 and 6 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 100866-82:
(8*1)+(7*0)+(6*0)+(5*8)+(4*6)+(3*6)+(2*8)+(1*2)=108
108 % 10 = 8
So 100866-82-8 is a valid CAS Registry Number.

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100866-82-8Relevant academic research and scientific papers

An improved Pfitzinger reaction: Eco-efficient synthesis of quinaldine-4-carboxylates by TMSCl-mediated

Lu, Lingling,Zhou, Pan,Hu, Biao,Li, Xiang,Huang, Rong,Yu, Fuchao

, p. 3658 - 3661 (2017)

We report herein an improved Pfitzinger reaction for the synthesis of highly functionalized quinaldines from 1,3-dicarbonyl compounds, isatins and alcohols mediated by TMSCl. This synthesis involves cyclization and esterification in one-step cascade process for the formation of a carboxylate (CO2R) at the 4-position of quinaldine ring. Moreover, this procedure shows highly efficient, good functional group tolerance, operational simplicity, environment-friendly and feasibility of scale up.

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