100869-93-0Relevant articles and documents
KF-alumina-mediated selective double Michael additions of aryl methyl ketones: A facile entry to the synthesis of functionalized pimelate esters and derivatives
Basu, Basudeb,Das, Pralay,Hossain, Ismail
, p. 2224 - 2226 (2004)
Here we describe simple and efficient double Michael additions of aromatic and aliphatic methyl ketones to electron deficient alkenes promoted on a surface of KF-alumina. This one-pot procedure provides an easy access to a host of functionalized pimelate
Enviornmentally benign michael and claisen schmidt reaction of aromatic carbonyl compounds by alkaline polyionic resin
Jaitak, Vikas,Kaul,Das, Pralay
, p. 1137 - 1145 (2013/09/24)
A regioselective Michael reaction between aryl methyl ketones and α,β-unsaturated compounds has been carried out using basic polyionic resin as a reusable reagent. Results indicate that the reaction proceeds in consecutive manner as double Michael (27-65%) and triple Michael (40-45%) products with overall yields of 55-80%. Moreover, A-2XMP resin has also been applied on Claisen Schmidt condensations of aromatic aldehydes and ketones (acyclic as well as cyclic) under different reaction conditions yielding dehydrated products in 82-94% yield. The reactions give an opportunity for easy separation, reusability of polyionic resin and easy purification of products in continuous or multiple processing of organic compounds.
One-pot multicomponent Michael and Thorpe-Ziegler reaction of aryl methyl ketones
Jaitak, Vikas,Bandna,Das, Pralay,Kaul,Singh, Bikram,Kumar, Neeraj
experimental part, p. 2727 - 2737 (2011/09/15)
A regioselective base-promoted Michael and Thorpe-Ziegler reaction between aryl methyl ketones and αβ-unsaturated nitrile was carried out in a single step. Different functional groups in addition to active positions were tolerated under this condition. Re
