1008993-11-0Relevant academic research and scientific papers
Pd-Catalyzed C(sp3)-H Carbonylation of Alkylamines: A Powerful Route to γ -Lactams and γ-Amino Acids
Wang, Pei-Long,Li, Yan,Wu, Yun,Li, Chao,Lan, Quan,Wang, Xi-Sheng
, p. 3698 - 3701 (2015)
A novel Pd-catalyzed direct C(sp3)-H carbonylation of alkylamines for the synthesis of-lactams and -amino acids has been developed, in which TEMPO was used as the crucial sole oxidant. The synthetic prospect was demonstrated by the concise total synthesis of rac-Pregbalin.
