1009-79-6

Basic information

• Product Name: N-benzyl-2-mercapto acetamide
• Synonyms: N-benzyl-2-mercapto acetamide
• CAS NO: 1009-79-6
• Molecular Weight: 181.258
• Mol File: 1009-79-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: N-benzyl-2-mercapto acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-benzyl-2-mercapto acetamide(1009-79-6)
• EPA Substance Registry System: N-benzyl-2-mercapto acetamide(1009-79-6)

Safety Data

• Hazardous Substances Data: 1009-79-6(Hazardous Substances Data)

Upstream product

• 100-46-9 benzylamine 
• 68-11-1 mercaptoacetic acid 
• 1047-94-5 Bis-(N-benzyl-carbamoylmethyl)-disulfid 
• 88419-02-7 3-(2-(4-bromophenyl)-2-oxoethyl)thiazolidine-2,4-dione 
• 20938-74-3 mercapto-acetic acid methylamide 

Downstream Products

• 1363300-99-5 (2R,3S,4S,5R)-2-[2-(N-benzyl-2-acetamidyl)sulfanyl-ethyl]-3,4,5-trihydroxy-piperidine hydrochloride 
• 1439377-90-8 4-benzyl-7-(tetrahydro-2H-pyran-2-yl)-2H-pyridazino[4,5-b][1,4]thiazine-3,8(4H,7H)-dione 
• 1400566-13-3 4-benzyl-7-(trifluoromethyl)-2H-pyrido[3,2-b][1,4]thiazin-3(4H)-one 
• 1400566-12-2 4-benzyl-7-nitro-2H-benzo[b][1,4]thiazin-3(4H)-one 
• 1400566-11-1 4-benzyl-3-oxo-3,4-dihydro-2H-benzo[1,4]thiazine-7-carbonitrile 
• 67824-24-2 3-benzyl-thiazolidine 
• 67824-12-8 3-benzyl-thiazolidin-4-one 

Relevant articles and documents

β-GLUCOCEREBROSIDASE CHAPERONES

The present application relates to compounds of the Formula (I): which are useful or the treatment of diseases in which the wild type or a mutant form of the enzyme β-glucocerebrosidase is implicated.

RECYCLIZATION REACTIONS. RECYCLIZATIONS OF 3-ACYLMETHYL-2,4-THIAZOLIDINEDIONES BY THE ACTION OF NUCLEOPHILES

Four directions were established and investigated in the recyclization of 3-acylmethyl-2,4-thiazolidinediones with the participation of the side chain at the cyclic nitrogen atom and the formation of substituted 2-imidazolones or 2-oxazolones (under the influence of ammonia or hydroxides respectively), 2,5-diarylpyrazines (under the influence of methylamine), 6-monosubstituted or 2,6-disubstituted 4,5-dihydro-1,2,4-triazin-3-ones, and 5-substituted 1-amino-2-imidazolones (under the influence of hydrazine and phenylhydrazine).The directions of recyclization with hydrazines are determined by the stereochemical configuration of the intermediate hydrazones; the E-hydrazones of 3-acylmethyl-2,4-thiazolidenediones are converted into 4,5-dihydro-1,2,4-triazin-3-ones, while the Z izomers are converted into 1-amino-2-imidazolones.