1009042-16-3

Basic information

• Product Name: 2-(2-hydroxyphenyl)-4,5-diphenyl-1-p-tolyl-1H-imidazole
• Synonyms: 2-(2-hydroxyphenyl)-4,5-diphenyl-1-p-tolyl-1H-imidazole
• CAS NO: 1009042-16-3
• Molecular Weight: 402.495
• Mol File: 1009042-16-3.mol

Chemical Properties

• CAS DataBase Reference: 2-(2-hydroxyphenyl)-4,5-diphenyl-1-p-tolyl-1H-imidazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-hydroxyphenyl)-4,5-diphenyl-1-p-tolyl-1H-imidazole(1009042-16-3)
• EPA Substance Registry System: 2-(2-hydroxyphenyl)-4,5-diphenyl-1-p-tolyl-1H-imidazole(1009042-16-3)

Safety Data

• Hazardous Substances Data: 1009042-16-3(Hazardous Substances Data)

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 106-49-0 p-toluidine 
• 90-02-8 salicylaldehyde 
• 134-81-6 benzil 

Relevant articles and documents

Design, synthesis, photophysical and electrochemical properties of 2-(4,5-diphenyl-1-p-aryl-1H-imidazol-2-yl)phenol-based boron complexes

New hybrid organic-inorganic boron compounds using an imidazole core have been readily synthesized by a two-step procedure from commercially available simple starting materials. All boron compounds were fully characterized by multinuclear NMR spectroscopy

A highly selective ratiometric detection of F-based on excited-state intramolecular proton-transfer (imidazole) materials

Inspired by the importance of fluoride ions in the field of dental fluorosis and treatment of osteoporosis, we have synthesized a probe 2 (2-(2-tert-butyldiphenylsiloxy)phenyl-4,5-diphenyl-1-p-tolyl-1H-imidazole) for the detection of fluoride ions from simple starting materials. The probe was characterized using standard analytical and spectroscopic techniques including single crystal X-ray crystallography. The probe (2) exhibited a multi-channel rapid response and excellent selectivity and sensitivity towards fluoride ions through selective cleavage of Si-O bonds. Time-dependant density functional theory (TD-DFT) calculations were carried out to vindicate the optical properties of the probe (2) and its starting material (compound 1).

Magnetic nanoparticle-supported sulfonic acid as a green catalyst for the one-pot synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions

In this work, magnetic nanoparticle-supported sulfonic acid (γ-Fe2O3-SO3H) is used as an efficient catalyst in the synthesis of 2,4,5-trisubstituted imidazoles and 1,2,4,5-tetrasubstituted imidazoles in a short time (40-70 min for trisubstituted imidazoles and 30-40 min for tetrasubstituted imidazoles) and high-purity products were obtained (92-98% for trisubstituted imidazoles and 94-98% for tetrasubstituted imidazoles) in simple multicomponent reactions. The structure of these products was confirmed via FT-IR and NMR. Green and recyclable catalysts, eco-friendly and solvent-free conditions, high catalytic activity, shorter reaction time, easy recovery by an external magnet, high purity, and excellent yields are some features of these reactions.

Ag–TiO2 nanocomposite-catalyzed one-pot synthesis of 1,2,4,5-tetrasubstituted imidazoles: a green and benign approach

Ag–TiO2 nanocomposite as an efficient catalyst was synthesized and characterized by AFM analysis. This nanocomposite acts as a heterogeneous and recyclable catalyst for the room temperature synthesis of 1,2,4,5-tetrasubstituted imidazoles from aldehydes, benzil, ammonium acetate and several anilines or aliphatic amines via one-pot four-component condensation reaction in H2O as a green solvent. Ag–TiO2 nanocomposite was simply recovered by filtration and was reused up to three times.

Solvent-free multicomponent reactions using the novel N-sulfonic acid modified poly(styrene-maleic anhydride) as a solid acid catalyst

A new N-sulfonic acid based on the polymer-support as a solid acid catalyst is prepared by the reaction of the modified poly(styrene-alt-maleic anhydride) with neat chlorosulfonic acid. 4H-Pyrimido[2,1-b]benzothiazole derivatives, tetrasubstituted imidazoles and benzoxanthenones as selected solvent-free multicomponent reactions were successfully synthesized using this catalyst. These eco-friendly protocols offer several advantages such as green and cost-effective procedures with excellent yield, shorter reaction time, simpler work-up, recovery, and reusability of metal-free solid acid heterogeneous catalyst along with tolerance of a wide range of functional groups.

Efficient multi-component synthesis of highly substituted imidazoles utilizing P2O5/SiO2 as a reusable catalyst

Phosphorus pentoxide supported on silica gel (P2O 5/SiO2) has been used as an efficient and reusable catalyst for the one-pot pseudo four-component synthesis of 2,4,5-trisubstituted imidazoles from benzil or benzoin, aldehydes, and ammonium acetate. It was also used for four-component preparation of 1,2,4,5-tetrasubstituted imidazoles from benzil or benzoin, aldehydes, primary amine, and ammonium acetate under thermal solvent-free conditions. The remarkable features of this new procedure are high conversions, cleaner reaction, simple experimental and work-up procedures and also the catalyst can be easily separated from the reaction mixture and reused several times without any loss of its activity.

Synthesis of highly substituted imidazoles using Bronsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl)phosphonium toluenesulfonate, as reusable catalyst

Bronsted acidic ionic liquid, triphenyl(propyl-3-sulphonyl) phosphonium toluenesulfonate, has been used as an efficient and reusable catalyst for the one-pot synthesis of 2,4,5-trisubstituted and 1,2,4,5-tetrasubstituted imidazoles under solvent-free conditions in excellent yields.

Physicochemical studies of molecular hyperpolarizability of imidazole derivatives

A series of substituted imidazoles have been synthesized in very good yield under solvent free condition by grinding 1,2-diketone, arylaldehyde, arylamine and ammonium acetate in the presence of molecular iodine as the catalyst. The short reaction time, g

An intramolecular charge transfer fluorescent probe: Synthesis, structure and selective fluorescent sensing of Cu+2

A series of substituted imidazoles have been synthesized in very good yield under solvent free condition by grinding 1,2-diketone, aromatic aldehyde and ammonium acetate in the presence of molecular iodine as the catalyst. The short reaction time, good yi