100914-71-4Relevant academic research and scientific papers
Intramolecular Direct Arylation of 3-Halo-2-pyrones and 2-Coumarins
Nolan, Marie-T.,Pardo, Leticia M.,Prendergast, Aisling M.,McGlacken, Gerard P.
, p. 10904 - 10913 (2015)
Direct arylation represents a favorable alternative to traditional cross-coupling and has found widespread use with simple aryls and robust heterocycles. Herein a direct arylation protocol has been optimized and applied to 2-pyrones, which are delicate an
Regioselective Chlorination and Suzuki–Miyaura Cross-Coupling of 4-Alkoxycoumarins, 4-Alkoxy-2-pyrones, and Related Heterocycles
Prendergast, Aisling M.,McGlacken, Gerard P.
, p. 4827 - 4835 (2017/09/07)
Chlorination of the coumarin framework was achieved by using trichloroisocyanuric acid, which has several advantages over N-chlorosuccinimide, particularly with respect to cost-effectiveness and toxicity. The Suzuki–Miyaura cross-coupling of the chlorinat
