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1-[(4-bromophenyl)methyl]-2-methylbenzimidazole is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

100915-23-9

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100915-23-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 100915-23-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,1 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 100915-23:
(8*1)+(7*0)+(6*0)+(5*9)+(4*1)+(3*5)+(2*2)+(1*3)=79
79 % 10 = 9
So 100915-23-9 is a valid CAS Registry Number.

100915-23-9Relevant academic research and scientific papers

Synthesis and biological evaluation of 4′-[(benzimidazole-1-yl) methyl]biphenyl-2-sulfonamide derivatives as dual angiotensin II/endothelin A receptor antagonists

Bai, Renren,Wei, Zhen,Liu, Jie,Xie, Weijia,Yao, Hequan,Wu, Xiaoming,Jiang, Jieyun,Wang, Qiujuan,Xu, Jinyi

, p. 4661 - 4667 (2012/09/07)

A series of 4′-[(benzimidazole-1-yl)methyl]biphenyl-2-sulfonamide derivatives (Ia-Il) were synthesized and biologically evaluated. It was found that Ig, the most active compound, antagonized both Ang II AT1 and endothelin ETA receptors (AT1 IC50 = 8.5, ETA IC50 = 8.9 nM), and was more potent than losartan in RHRs with no significant effect on heart rate. The preliminary structure-activity relationships were also discussed in the present paper.

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