1009378-52-2

Usage

Uses

Used in Organic Synthesis:
6-Chloropyrazine-2-boronic acid pinacol ester is used as a reagent for the formation of carbon-carbon and carbon-heteroatom bonds. It is commonly utilized in cross-coupling reactions and palladium-catalyzed coupling reactions to create complex organic molecules.
Used in Pharmaceutical Industry:
6-Chloropyrazine-2-boronic acid pinacol ester is used as a valuable building block for the construction of pharmaceuticals. Its pinacol ester structure provides stability and ease of handling in the laboratory, making it suitable for the synthesis of various medicinal compounds.
Used in Agrochemical Industry:
6-Chloropyrazine-2-boronic acid pinacol ester is also used as a building block for the synthesis of agrochemicals. Its versatility in forming different types of bonds makes it useful in the development of various agrochemical products.
Used in Materials Science:
6-Chloropyrazine-2-boronic acid pinacol ester is used in the synthesis of materials, where its ability to form carbon-carbon and carbon-heteroatom bonds is valuable for creating complex structures and functional materials.

Upstream product

• 4774-14-5 2,6-dichloropyrazine 
• 73183-34-3 bis(pinacol)diborane 

Relevant academic research and scientific papers

Nitrogen-containing heterocyclic derivative and organic electroluminescent device thereof

The invention provides a nitrogen-containing heterocyclic derivative and an organic electroluminescent device thereof, and belongs to the technical field of organic electroluminescence. The nitrogen-containing heterocyclic derivative has strong hole block

Efficient synthesis of pyrazine boronic esters via palladium-catalyzed Miyaura borylation

A facile and efficient protocol for palladium-catalyzed Miyaura borylation reaction of chloropyrazines with B2pin2has been developed. A certain range of difficult-to-access pyrazine boronic esters can be easily prepared from the corresponding chloropyrazines in moderate to good yields.

N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS

The present invention provides a compound of the general formula (1): wherein one of X and Y is N and the other is an optionally substituted carbon atom, and Z2-Z5 represent one or two nitrogen atoms, as further described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals and as components of pharmaceutical compositions. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds described herein or pharmaceutical compositions comprising such compounds.

PYRAZINYLPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The present invention provides a compound of Formula (I) and pharmaceutically acceptable salts thereof. Also provided is a method of using a compound of Formula I for treating a disease or condition mediated by a CDK inhibitor.