100944-88-5Relevant articles and documents
Synthese et activite biologique de prodrogues de l'acide oxolinique
Loubinoux, B,Colin, JL,Thomas, V
, p. 461 - 467 (2007/10/02)
Synthesis and biological activities of oxolinic acid pro-drugs.Antiseptic phenols, anti-inflammatory acids and polyethyleneglycol moieties have been attached by labile bonds to oxolinic acid giving pro-drugs with anti-bacterial activities.Some of them are more soluble in water, exhibit a more sustained action in the time and give higher plasma and tissue concentrations compared with the free drug.