1009588-79-7Relevant academic research and scientific papers
Synthesis and structure activity relationship studies of novel Staphylococcus aureus Sortase A inhibitors
Chenna, Bala Chandra,King, Jason R.,Shinkre, Bidhan A.,Glover, Amanda L.,Lucius, Aaron L.,Velu, Sadanandan E.
experimental part, p. 3752 - 3761 (2010/11/17)
Synthetic methods have been developed for lead Sortase A inhibitors identified from previous studies. Several derivatives of the lead inhibitor were synthesized to derive preliminary structure activity relationships (SAR). Different regions of the lead in
Identification of novel inhibitors of bacterial surface enzyme Staphylococcus aureus Sortase A
Chenna, Bala Chandra,Shinkre, Bidhan A.,King, Jason R.,Lucius, Aaron L.,Narayana, Sthanam V.L.,Velu, Sadanandan E.
, p. 380 - 385 (2008/04/03)
In-silico virtual screening of bacterial surface enzyme Staphylococcus aureus Sortase A against commercial compound libraries using FlexX software package has led to the identification of novel inhibitors. Inhibition of enzyme catalytic activity was deter
