100959-91-9 Usage
Uses
Used in Pharmaceutical Industry:
2-Methyl-1,3-thiazole-4-carboxamide is used as a reactant for the synthesis of bisthiazole-based histone deacetylase inhibitors. These inhibitors play a crucial role in the development of novel drugs targeting epigenetic modifications, which are often dysregulated in various diseases, including cancer. By modulating the activity of histone deacetylases, these inhibitors can potentially correct abnormal gene expression patterns and restore normal cellular functions.
Check Digit Verification of cas no
The CAS Registry Mumber 100959-91-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,5 and 9 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 100959-91:
(8*1)+(7*0)+(6*0)+(5*9)+(4*5)+(3*9)+(2*9)+(1*1)=119
119 % 10 = 9
So 100959-91-9 is a valid CAS Registry Number.
100959-91-9Relevant academic research and scientific papers
IRAK DEGRADERS AND USES THEREOF
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Paragraph 00803; 00129; 00132-00133, (2021/06/26)
The present invention provides compounds, compositions thereof, and methods of using the same.
IRAK DEGRADERS AND USES THEREOF
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Paragraph 00920; 002780; 002783-002784, (2021/01/23)
The present invention provides compounds, compositions thereof, and methods of using the same. The compounds include an IRAK binding moiety capable of binding to IRAK4 and a degradation inducing moiety (DIM). The DIM could be DTM a ligase binding moiety (LBM) or lysine mimetic. The compounds could be useful as IRAK protein kinase inhibitors and applied to IRAK mediated disorders.
