10200-43-8

Basic information

• Product Name: 2-methyl oxazole 4-ethyl ester
• Synonyms: ETHYL-4-METHYL-3,5-OXAZOLECARBOXYLATE;2-methyl oxazole 4-ethyl ester;2-Methyl-4-oxazolecarboxylic acid ethyl ester;Ethyl 2-methyl-4-oxazolecarboxylate;4-(Ethoxycarbonyl)-2-methyl-1,3-oxazole;Ethyl 2-methyl-1,3-oxazole-4-carboxylate;2-Methyl-oxazole-4-carboxylic acid ethyl ester
• CAS NO: 10200-43-8
• Molecular Formula: C₇H₉NO₃
• Molecular Weight: 155.15
• Mol File: 10200-43-8.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 210.361 °C at 760 mmHg
• Flash Point: 81.023 °C
• Appearance: /
• Density: 1.14 g/cm³
• Vapor Pressure: 0.193mmHg at 25°C
• Refractive Index: 1.468
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-methyl oxazole 4-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl oxazole 4-ethyl ester(10200-43-8)
• EPA Substance Registry System: 2-methyl oxazole 4-ethyl ester(10200-43-8)

Safety Data

• Hazardous Substances Data: 10200-43-8(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C7H9NO3/c1-3-10-7(9)6-4-11-5(2)8-6/h4H,3H2,1-2H3

Upstream product

• 74-88-4 methyl iodide 
• 60-35-5 acetamide 
• 70-23-5 ethyl Bromopyruvate 
• 23012-14-8 oxazole-4-carboxylic acid ethyl ester 
• 617-35-6 2-oxo-propionic acid ethyl ester 
• 109-94-4 formic acid ethyl ester 
• 108-24-7 acetic anhydride 
• 61999-29-9 2-Methyl-4,5-dihydro-1,3-oxazole-4-carboxylic acid ethyl ester 
• 14762-48-2 ethyl 2-diazo-3-oxo-propanoate 
• 75-05-8 acetonitrile 
• 68683-04-5 ethyl (2-methyl-2-oxazolin-4-yl)carboxylate 
• 142-71-2 copper diacetate 
• 7787-70-4 copper(I) bromide 

Downstream Products

• 62348-22-5 2-methyl-1,3-oxazole-4-carboxylic acid chloride 
• 187269-86-9 2'-Methyl-2,4'-bi(1,3-oxazoyl)-4-carboxylic acid methyl ester 
• 301155-42-0 2'-Methyl-4-phenylselenyl-4,5-dihydro-2,4'-bi(1,3-oxazoyl)-4-carboxylic acid methyl ester 
• 301155-47-5 2''-Methyl-4-phenylselenyl-4,5-dihydro-2,4':2',4''-teroxazole-4-carboxylic acid methyl ester 
• 113732-84-6 2-methyl-1,3-oxazole-4-carbaldehyde 
• 875553-59-6 N-methoxy-N-methyl-2-methyloxazole-4-carboxamide 
• 141567-53-5 4-hydroxymethyl-2-methyloxazole 
• 100872-45-5 4-[4-(4-methoxy-phenyl)-thiazol-2-yl]-2-methyl-oxazole 
• 96461-28-8 2-methyl-4-[4-(4-nitro-phenyl)-thiazol-2-yl]-oxazole 
• 96462-75-8 4-[4-(4-bromo-phenyl)-thiazol-2-yl]-2-methyl-oxazole 
• 96583-11-8 4-[4-(4-chloro-phenyl)-thiazol-2-yl]-2-methyl-oxazole 
• 100872-18-2 2-methyl-4-(4-p-tolyl-thiazol-2-yl)-oxazole 
• 106166-86-3 2-methyl-4-(4-phenyl-thiazol-2-yl)-oxazole 
• 90980-10-2 2-methyl-oxazole-4-carbothioic acid amide 

Relevant articles and documents

DIRECT PREPARATION OF 4-CARBOETHOXY-1,3-OXAZOLES

The diazoaldehyde ester N2C(CHO)CO2Et undergoes rhodium-catalyzed reaction with nitriles to give 4-carboethoxy-1,3-oxazoles directly.

Facile synthesis of oxazoles starting from ketones

A new and efficient method for the preparation of 2,4- and 2,4,5-substituted oxazoles is described which is based upon the reaction of α-sulfonyloxy ketone intermediates with acetamide or benzamide.

Direct palladium-catalyzed alkenylation, benzylation and alkylation of ethyl oxazole-4-carboxylate with alkenyl-, benzyl- and alkyl halides

The ethyl oxazole-4-carboxylate was directly and regioselectively alkenylated, benzylated and alkylated with alkenyl-, benzyl-, allyl- and alkyl halides in the presence of catalytic amounts of palladium acetate with caesium carbonate using Buchwald's John

Atropisomers of 3-heteroaryl-4(3H)-quinazolinones for the treatment of neurodegenerative and CNS-trauma related conditions

The present invention relates to novel atropisomers of 3-heteroaryl-4(3H)-quinazolinones of the formula Ia, and their pharmaceutically acceptable salts, and pharmaceutical compositions and methods of treating neurodegenerative and CNS-trauma related conditions.