1009605-85-9

Basic information

• Product Name: (2R,5R)-3-tert-butyl-5-phenyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-2-ol
• Synonyms: (2R,5R)-3-tert-butyl-5-phenyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-2-ol
• CAS NO: 1009605-85-9
• Molecular Weight: 301.309
• Mol File: 1009605-85-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,5R)-3-tert-butyl-5-phenyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,5R)-3-tert-butyl-5-phenyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-2-ol(1009605-85-9)
• EPA Substance Registry System: (2R,5R)-3-tert-butyl-5-phenyl-2-(trifluoromethyl)-5,6-dihydro-2H-1,4-oxazin-2-ol(1009605-85-9)

Safety Data

• Hazardous Substances Data: 1009605-85-9(Hazardous Substances Data)

Upstream product

• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 175226-69-4 (5R)-3-tert-butyl-5-phenyl-5,6-dihydro-2H-1,4-oxazin-2-one 

Downstream Products

• 1009605-96-2 (2R,3R)-1,1,1-trifluoro-3-((R)-2-hydroxy-1-phenylethylamino)-4,4-dimethylpentan-2-ol 

Relevant articles and documents

An efficient entry to optically active anti- and syn-β-amino-α- trifluoromethyl alcohols

The reaction of chiral 5,6-dihydro-2H-1,4-oxazin-2-ones with TMSCF 3 in the presence of a suitable activator leads to trifluoromethyl lactols, which can be selectively reduced to anti-β-amino-α- trifluoromethyl alcohols. The corresponding syn d