1009640-88-3

Upstream product

• 88013-15-4 2-bromo-6-phenylimidazo<2,1-b>-1,3,4-thiadiazole 

Downstream Products

• 1009640-91-8 5-bromo-6-phenyl-2-piperidin-1-ylimidazo[2,1-b][1,3,4]thiadiazole 
• 1009640-92-9 5-bromo-2-morpholin-4-yl-6-phenylimidazo[2,1-b][1,3,4]thiadiazole 
• 1009640-93-0 (5-bromo-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-hydrazine 
• 1009640-90-7 (5-bromo-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-dimethylamine 
• 1009640-89-4 (5-bromo-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-yl)-methylamine 

Relevant academic research and scientific papers

Preparation of 5-bromo-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-ylamines

(Chemical Equation Presented) The reaction of primary or secondary amines with 2,5-dibromo-6-phenylimidazo[2,1-b][1,3,4]-thiadiazole (5) leads to a chemoselective replacement of the 2-Br substituent. The process represents a convenient route to the corresponding 2-ylamines 7a-d. Hydrazine reacts in an analogous fashion (5 → 7e). The structure determinations are based on an X-ray crystal structure analysis and on one- and two-dimensional NMR measurements.

Synthesis and properties of (6-methyl-2-oxo-4-thioxo-1,2,3,4-tetrahydro-3- pyrimidinyl)acetic acid methyl ester

2-amino-5-bromo-1,3,4-thiadiazole, 2-bromo-6-phenyl-imidazo[2,1-b]-1,3,4- thiadiazole, 2,5-dibromo-6-phenylimidazo[2,1-b]-1,3,4-thiadiazole, 2-morpholino-5-morpholinomethyl-6-phenylimidazo[2,1-b]-1,3,4-thiadiazole.