1009640-89-4Relevant academic research and scientific papers
Preparation of 5-bromo-6-phenylimidazo[2,1-b][1,3,4]thiadiazol-2-ylamines
Safarov, Saifidin,Rahmon, Rahmonov,Kukaniev, Muhamacho Amadovich,Schollmeyer, Dieter,Karpuk, Elena,Meier, Herbert
, p. 299 - 302 (2008/09/19)
(Chemical Equation Presented) The reaction of primary or secondary amines with 2,5-dibromo-6-phenylimidazo[2,1-b][1,3,4]-thiadiazole (5) leads to a chemoselective replacement of the 2-Br substituent. The process represents a convenient route to the corresponding 2-ylamines 7a-d. Hydrazine reacts in an analogous fashion (5 → 7e). The structure determinations are based on an X-ray crystal structure analysis and on one- and two-dimensional NMR measurements.
