100967-69-9Relevant academic research and scientific papers
Study on the kinetics of the reaction between diethyl ester of 1-amino-methyl-ethanephosphonic acid and phenyl isocyanate
Alexiev, Alexi,Lachkova, Victoria,Petrov, Galin
, p. 191 - 199 (1997)
The kinetics of the reaction between O,O-diethyl ester of 1-amino-1-methyl-ethane phosphonic acid and phenylisocyanate, producing diethyl ester of 1-methyl-1-(N-phenylcarbamoyl-amino)ethane phosphonic acid is studied by IR spectroscopy. It is established that the reaction is of second order. The probable scheme of the reaction mechanism is suggested. The rate constant k of the initial stage of the reaction is determined. It is established that the rate constant is increased at the advanced stage of the process. The observed enhancement is ascribed to the autocalalytic effect of the reaction product.
SYNTHESIS OF 1-METHYL-1-(N-SUBSTITUTED CARBAMOYL- AND THIOCARBAMOYL-AMINO) ALKANEPHOSPHONIC ACIDS-DIETHYL ESTERS
Lachkova, Victoria I.,Petrov, Galin,Hussein, Ali H.
, p. 161 - 168 (2007/10/02)
Diethylesters of 1-methyl-1-(N-substituted carbamoyl- or thiocarbamoyl-amino)-alkane-phosphonic acids are obtained by interaction of O,O-diethyl esters of 1-amino-1-methyl-alkanephosphonic acids and different isocyanates or isothiocyanates at room tempera
