100972-79-0

Basic information

• Product Name: 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester
• Synonyms: 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester
• CAS NO: 100972-79-0
• Molecular Weight: 266.294
• Mol File: 100972-79-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester(100972-79-0)
• EPA Substance Registry System: 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester(100972-79-0)

Safety Data

• Hazardous Substances Data: 100972-79-0(Hazardous Substances Data)

Upstream product

• 13788-90-4 3,3-dimethoxy-1-phenylpropan-1-one 
• 96-34-4 methyl chloroacetate 

Downstream Products

• 934340-08-6 C₁₂H₉BrO₃ 
• 934340-50-8 C₁₉H₁₅ClO₄ 
• 71237-44-0 methyl 3-phenyl-2-furoate 

Relevant articles and documents

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

The C-3 substituents effect on NHE-1 inhibitory activity of (5-arylfuran-2-ylcarbonyl)guanidines, previously identified as potent NHE-1 inhibitors, was investigated. The introduction of amine or alkyl groups at the 3-position of the furan ring, next to the acylguanidine moiety, remarkably improves NHE-1 inhibitory potency. Especially the important finding is that 5-(2,5-dichloro)phenyl and 5-(2-methoxy-5-chloro)phenyl derivatives exhibit high NHE-1 inhibitory activities (IC50 0.02 μM) that match those of 3-unsubstituted derivatives.