71237-44-0

Basic information

• Product Name: methyl 3-phenyl-2-furoate
• Synonyms: methyl 3-phenyl-2-furoate
• CAS NO: 71237-44-0
• Molecular Weight: 202.21
• Mol File: 71237-44-0.mol

Chemical Properties

• CAS DataBase Reference: methyl 3-phenyl-2-furoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-phenyl-2-furoate(71237-44-0)
• EPA Substance Registry System: methyl 3-phenyl-2-furoate(71237-44-0)

Safety Data

• Hazardous Substances Data: 71237-44-0(Hazardous Substances Data)

Upstream product

• 100972-79-0 2,3-epoxy-5,5-dimethoxy-3-phenyl-valeric acid methyl ester 
• 14903-90-3 3-bromofuran-2-carboxylic acid 
• 59862-77-0 methyl 3-bromofuran-2-carboxylate 
• 98-80-6 phenylboronic acid 
• 13788-90-4 3,3-dimethoxy-1-phenylpropan-1-one 

Downstream Products

• 169772-63-8 3-phenyl-2-furoic acid 
• 78646-98-7 4-(2-oxo-3,3a,8,8a-tetrahydro-2H-indeno<2,1-b>furan-3-ylidenemethoxy)-2-phenylbut-2-en-4-olide 
• 78646-91-0 4-(2-oxo-3,3a,6,6a-tetrahydro-2H-cyclopentafuran-3-ylidenemethoxy)-2-phenylbut-2-en-4-olide 
• 78646-62-5 4-chloro-2-phenylbut-2-en-4-olide 
• 66661-71-0 4-hydroxy-2-phenylbut-2-en-4-olide 
• 934340-50-8 C₁₉H₁₅ClO₄ 
• 934340-08-6 C₁₂H₉BrO₃ 

Relevant articles and documents

CALPAIN MODULATORS AND THERAPEUTIC USES THEREOF

Disclosed herein are small molecule calpain modulator compositions, pharmaceutical compositions, the use and preparation thereof.

3-Substituted-(5-arylfuran-2-ylcarbonyl)guanidines as NHE-1 inhibitors

The C-3 substituents effect on NHE-1 inhibitory activity of (5-arylfuran-2-ylcarbonyl)guanidines, previously identified as potent NHE-1 inhibitors, was investigated. The introduction of amine or alkyl groups at the 3-position of the furan ring, next to the acylguanidine moiety, remarkably improves NHE-1 inhibitory potency. Especially the important finding is that 5-(2,5-dichloro)phenyl and 5-(2-methoxy-5-chloro)phenyl derivatives exhibit high NHE-1 inhibitory activities (IC50 0.02 μM) that match those of 3-unsubstituted derivatives.