1009839-34-2Relevant academic research and scientific papers
A general route to cyclopeptide alkaloids: total syntheses and biological evaluation of paliurines e and F, ziziphines N and Q, abyssenine A, mucronine E, and analogues
Toumi, Mathieu,Rincheval, Vincent,Young, Ashley,Gergeres, Danielle,Turos, Edward,Couty, Francois,Mignotte, Bernard,Evano, Gwilherm
experimental part, p. 3368 - 3386 (2011/02/28)
A full account of the total syntheses of the cyclopeptide alkaloids paliurine E and F, ziziphine N and Q, abyssenine A, and mucronine E is provided. A key feature of the syntheses involves an intramolecular amidation of a vinyl iodide, which allows us sim
Total synthesis of the cyclopeptide alkaloid paliurine E. insights into macrocyclization by ene-enamide RCM
Toumi, Mathieu,Couty, Francois,Evano, Gwilherm
, p. 1270 - 1281 (2008/09/16)
(Chemical Equation Presented) The total synthesis of (-)-paliurine E is described in 14 steps and 11% overall yield. The first successful application of ene-enamide ring-closing metathesis for macrocyclization serves as the foundation for this synthesis a
