100987-89-1 Usage
Uses
Used in Pharmaceutical Research:
5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE is used as a research compound for the development of new drugs. Its unique structural features make it a promising candidate for medicinal chemistry, where it can be studied for its potential pharmacological effects and therapeutic applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE is used as a building block for the synthesis of novel therapeutic agents. Its heterocyclic nature and structural properties can be leveraged to design and develop new drugs with improved efficacy and safety profiles.
Used in Drug Development:
5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE is used as a starting material in drug development processes. Its potential applications in treating various health conditions make it a valuable asset in the search for new pharmaceuticals that can address unmet medical needs.
Used in Safety and Toxicology Studies:
Due to its potential health risks, 5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE is also used in safety and toxicology studies to evaluate its effects on living organisms and to establish appropriate safety protocols for its handling and use in research and development.
Note: Since the provided materials do not specify particular applications or industries for 5-(4-ISOPROPYLPHENYL)-1,3,4-THIADIAZOL-2-AMINE, the uses listed above are general and based on the compound's potential in medicinal chemistry and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 100987-89-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,9,8 and 7 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 100987-89:
(8*1)+(7*0)+(6*0)+(5*9)+(4*8)+(3*7)+(2*8)+(1*9)=131
131 % 10 = 1
So 100987-89-1 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3S/c1-7(2)8-3-5-9(6-4-8)10-13-14-11(12)15-10/h3-7H,1-2H3,(H2,12,14)
100987-89-1Relevant academic research and scientific papers
PhI-Catalyzed Intramolecular Oxidative Coupling Toward Synthesis of 2-Amino-1,3,4-Thiadizoles
Han, Yingzhi,Sun, Yadong,Abdukader, Ablimit,Liu, Bifu,Wang, Duozhi
, p. 3486 - 3491 (2018/09/27)
A highly efficient method for the synthesis of thiadiazole derivatives via intramolecular oxidative coupling of thiosemicarbazide, using the in situ generated hypervalent iodine(III) reagents is developed. The protocol can be carried out smoothly and provides a variety of thiadiazole derivatives in moderate to excellent yields. Graphical Abstract: A highly efficient method for the synthesis of thiadiazole derivatives via PhI-catalyzed intramolecular oxidative coupling of thiosemicarbazide has been developed.
Synthesis and antiallergy activity of [1,3,4]thiadiazolo[3,2-a]-1,2,3-triazolo[4,5-d]pyrimidin-9(3H)-one derivatives. I
Suzuki,Miwa,Aibara,Kanno,Takamori,Tsubokawa,Ryokawa,Tsukada,Isoda
, p. 357 - 363 (2007/10/02)
A series of 6-substituted [1,3,4]thiadiazolo[3,2-a]-1,2,3-triazolo[4,5-d]pyrimidin-9(3H)-one derivatives 4a-z were synthesized from 5-substituted-1,3,4-thiadiazol-2-amines 5 by the following consecutive reactions: pyrimidine ring closure with bis(2,4,6-trichlorophenyl) malonate, nitration, chlorination, amination, hydrogenation and diazotization. The structure of 4 was confirmed by an alternate synthesis of 4, involving reaction of 5-substituted 2-azido-1,3,4-thiadiazole 13 with ethyl cyanoacetate, followed by the Dimroth rearrangement and ring closure. The antiallergic activities (anti-passive peritoneal anaphylaxis, anti-passive cutaneous anaphylaxis and anti-slow reacting substance of anaphylaxis activities) of the products were evaluated.
