100989-35-3Relevant academic research and scientific papers
Synthesis of long-chain 2-alkadiynylpyridines
Fedenok,Plashchenyuk,Myasnikova,Shvartsberg
, p. 667 - 670 (1996)
Four pathways of synthesis of 1-(2-pyridyl)heptacosa-12,14-diyne, using 10-bromodecan-1-ol and acetylene or tetradec-1-yne and 2-methylbut-3-yn-2-ol along with α-picoline as initial compounds, were studied and compared. It was shown that direct introduction of a completely formed unsaturated hydrocarbon chain into an α-picoline molecule by alkylation of its lithium derivative is the most appropriate method for preparation of long-chain 2-alkadiynylpyridines.
