100997-46-4

Usage

Derivative of indole

A modified version of the parent compound indole, which is a heterocyclic aromatic organic compound.

Physical appearance

Yellow crystalline solid
The compound has a yellow color and a crystalline structure when in its solid state.

Use in organic synthesis

The compound is commonly used as a key intermediate in the production of various chemicals, including pharmaceuticals, agrochemicals, and other fine chemicals.

Biological activities

Exhibits potential antitumor and antifungal properties, making it a valuable compound for research and development in the pharmaceutical industry.

Upstream product

• 119-53-9 2-hydroxy-2-phenylacetophenone 
• 10272-07-8 3.5-dimethoxyaniline 
• 91107-10-7 4,6-dimethoxy-2,3-diphenyl-1H-indole 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 123846-60-6 7,9-dimethoxy-1,2-diphenyl-4-oxo-4H-pyrrolo<3,2,1-ij>quinoline 
• 100851-85-2 ((CH)C₈HN(C₆H₅)2(OCH₃)2)2(C₆H₄N₂)Ni 

Relevant academic research and scientific papers

Synthesis and structural analysis of novel indole derivatives by XRD, spectroscopic and DFT studies

The indole derivatives have been getting immense interest to possess diverse applications in different fields. In present investigation, four novel indole based derivatives namely; 4,6-dimethoxy-2,3-diphenyl-1H-indole 3a, 4,5,6-trimethoxy-2,3-diphenyl-1H-

Synthesis, characterization, UV–Vis absorption and cholinesterase inhibition properties of bis-indolyl imine ligand systems

A number of bis-indolyl imine helical structures has successfully been synthesized employing Schiff base reaction conditions starting from 4,6-dimethoxy-2,3-diphenylindole with different o-phenyl diamines as π-spacer bridged. The structures of targeted co

Synthesis and antioxidant screening of Novel indole amines

Novel indoles amines have been synthesized and screened for antioxidant activity. Chiron approach is used to synthesis enantiopure heterocycles. Newly synthesized indole amines showed good antioxidant potential as compared to standard drugs. Novel indole

Ring closing metathesis strategies towards functionalised 1,7-annulated 4,6-dimethoxyindoles

A ring closing metathesis approach has been used to prepare a novel range of indoles 1,7-annulated with nitromethyl and lactone functionalised medium-sized rings. Initial studies into the preparation of lactam functionalised rings are also discussed.

Synthesis of novel 1,7-annulated 4,6-dimethoxyindoles

A range of new 1,7-annulated indole derivatives has been prepared via a ring-closing metathesis approach starting from N-allyl-7-formyl indoles.

Synthesis of 2-(7-Indolyl)-benzimidazoles via 7-Formylindoles

4,6-Dimethoxyindoles undergo Vilsmeier formylation to give 7-formylindoles which can be converted into 2-(7-indolyl)-benzimidazoles on reaction with 1,2-diaminobenzene.