101-01-9

Basic information

• Product Name: 1,2,3-TRIPHENYLGUANIDINE
• Synonyms: 1,2,3-trifenylguanidin;1,2,3-triphenyl-guanidin;n,n’,n’’-triphenyl-guanidin;N,N',N''-TRIPHENYLGUANIDINE;TRIPHENYLGUANIDINE;A-TRIPHENYLGUANIDINE;1,2,3-TRIPHENYLGUANIDINE;«
• CAS NO: 101-01-9
• Molecular Formula: C₁₉H₁₇N₃
• Molecular Weight: 287.36
• EINECS: 202-907-9
• Mol File: 101-01-9.mol
• Article Data: 14

Chemical Properties

• Melting Point: 146-147°C
• Boiling Point: 419.66°C (rough estimate)
• Appearance: /
• Density: 1,16 g/cm3
• Refractive Index: 1.5800 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• PKA: 9.10±0.10(Predicted)
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 1,2,3-TRIPHENYLGUANIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3-TRIPHENYLGUANIDINE(101-01-9)
• EPA Substance Registry System: 1,2,3-TRIPHENYLGUANIDINE(101-01-9)

Safety Data

• Statements: 36/37/38-22
• Safety Statements: 26-36/37/39-36/37
• RTECS: MF6825000
• TSCA: Yes
• Hazardous Substances Data: 101-01-9(Hazardous Substances Data)

Usage

Chemical Properties

White, crystalline powder. Combustible.

Uses

Different sources of media describe the Uses of 101-01-9 differently. You can refer to the following data:
1. It is employed as a intermediate for organic synthesis.
2. Accelerator for vulcanization of rubber.

Purification Methods

Crystallise the guanidine from EtOH or EtOH/water. Dry it in vacuo.[Beilstein 12 H 451, 12 I 261, 12 II 246, 12 III 907, 12 IV 866.]

Upstream product

• 3898-08-6 1,1-diphenylthiourea 
• 62-53-3 aniline 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 102-08-9 N,N-diphenylthiourea 
• 102-07-8 bis(diphenyl)urea 
• 64-17-5 ethanol 
• 142-04-1 aniline hydrochloride 
• 5416-30-8 N,N'-diphenyl-S-methyl isothiourea 
• 2428-17-3 1,2-diaminoguanidine hydriodide 
• 72885-89-3 3-phenylimino-3H-benzimidazo<2,1-c><1,2,4>-dithiazole 
• 56-23-5 tetrachloromethane 
• 14213-16-2 5-methyl-1-phenyl-1H-tetrazole 
• 124-38-9 carbon dioxide 
• 7719-12-2 phosphorus trichloride 

Downstream Products

• 14124-22-2 2-(Phenylimino)-1,3-diphenyl-1,3-diazetidin-4-one 
• 4250-94-6 7-anilino-6-(4-tolyl)-5,12-diazabenzanthracene 
• 77903-04-9 N¹,N²,N³,N⁴,N⁵-Pentaphenylbiguanide 
• 751-59-7 (6-naphthalen-2-yl-dibenzo[b,h][1,6]naphthyridin-7-yl)-phenyl-amine 
• 102-08-9 N,N-diphenylthiourea 
• 149-30-4 2-thioxo-3H-1,3-benzothiazole 
• 124-38-9 carbon dioxide 
• 62-53-3 aniline 
• 103-72-0 phenyl isothiocyanate 
• 5416-43-3 (5-anilino-2,4-diphenyl-2,4-dihydro-[1,2,4]triazol-3-ylidene)-phenyl-amine 
• 107263-37-6 7-anilino-6-phenyl-5,12-diazabenzanthracene 
• 622-16-2 1,3-Diphenylcarbodiimide 
• 102-07-8 bis(diphenyl)urea 

Relevant articles and documents

Novel Desulphurization of Thiourea Derivatives by Alkaline Autoxidation

Autoxidation of 1,3-disubstituted thioureas in the presence of oxygen and tertiary butoxide in tertiary butanol afforded the corresponding ureas in good yields together with small amounts of the corresponding guanidines while the same treatment of benz- or naphth-imidazole-2-thiones gave the parent imidazoles and the 2-sulphonic acids.

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O-Iodoxybenzoic acid mediated oxidative condensation: Synthesis of guanidines using 1,-3-disubstituted thiourea precursors

An efficient and mild oxidative condensation procedure using o-iodoxybenzoic acid and triethylamine or ammonia as base has been developed for the synthesis of guanidines starting from easily synthesizable 1,3-disubstituted thioureas and amines or ammonia.

Benzenetellurinic Mixed Anhydrides as Mild Oxidizing Agents

Three benzenetellurinic mixed anhydrides. i. e. benzenetellurinyl acetate, trifluoroacetate, and trifluoromethanesulfonate, have been found to be mild oxidizing agents for various substrates such as thiol, phosphine, acyloin, α-hydroxy ester, catechol, hydroquinone, thiourea, and thioamide.The reactions towards the last two substrates are highly chemoselective, depending on both the reagent and substrate.