1010128-58-1 Usage
General Description
3-(1H-2-indolyl)-4-(4-methoxyphenyl)-1-methyl-1H-2-quinolinone is a chemical compound that is a derivative of quinolinone. It contains an indolyl group, a methyl group, and a methoxyphenyl group attached to the quinolinone backbone. 3-(1H-2-INDOLYL)-4-(4-METHOXYPHENYL)-1-METHYL-1H-2-QUINOLINONE has potential pharmaceutical applications due to its structural features, which may contribute to its ability to interact with biological systems. It is important to note that this chemical should be handled and used with caution, as its specific properties and potential uses will depend on the intended application and the nature of the research or development project in which it is being used.
Check Digit Verification of cas no
The CAS Registry Mumber 1010128-58-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,0,1,2 and 8 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1010128-58:
(9*1)+(8*0)+(7*1)+(6*0)+(5*1)+(4*2)+(3*8)+(2*5)+(1*8)=71
71 % 10 = 1
So 1010128-58-1 is a valid CAS Registry Number.
1010128-58-1Relevant articles and documents
Synthesis of 1H-indol-2-yl-(4-aryl)-quinolin-2(1H)-ones via Pd-catalyzed regioselective cross-coupling reaction and cyclization
Wang, Zhiyong,Wu, Jie
, p. 1736 - 1742 (2008/09/17)
An efficient and novel route for the synthesis of 1H-indol-2-yl-(4-aryl)-quinolin-2(1H)-one 1 via palladium-catalyzed site-selective cross-coupling reaction and cyclization process was described. Reaction of 3-bromo-4-trifloxy-quinolin-2(1H)-one 3 with arylboronic acid catalyzed by PdCl2(PPh3)2 afforded 3-bromo-4-aryl-quinolin-2(1H)-one 4, which then reacted with 2-ethynylaniline 5 via Pd-catalyzed Sonogashira coupling and CuI-mediated cyclization leading to the desired 1H-indol-2-yl-(4-aryl)-quinolin-2(1H)-one 1 in good yields.
