101033-24-3Relevant academic research and scientific papers
Thermal-induced dimerization cyclization of ethyl N-(styrylcarbamoyl) acetates: Formation of 4-hydroxy-2(1H)-pyridone-3- carboxamide derivatives
Zhao, Sheng-Yin,Liu, Bao-Shuo,Huang, Jing,Cheng, Shao-Hua,Deng, Yun-Xia,Shao, Zhi-Yu
, p. 2066 - 2075 (2014/07/07)
Thermal-induced dimerization cyclization of ethyl N-(styrylcarbamoyl) acetate derivatives has been investigated, leading to 4-hydroxy-2(1H)-pyridone- 3-carboxamide derivatives with good yields in diphenyl ether on 200-210 °C. Ethyl N-(styrylcarbamoyl)acet
Discovery of potent, selective, orally active, nonpeptide inhibitors of human mast cell chymase
Greco, Michael N.,Hawkins, Michael J.,Powell, Eugene T.,Almond Jr., Harold R.,De Garavilla, Lawrence,Hall, Jeffrey,Minor, Lisa K.,Wang, Yuanping,Corcoran, Thomas W.,Di Cera, Enrico,Cantwell, Angelene M.,Savvides, Savvas N.,Damiano, Bruce P.,Maryanoff, Bruce E.
, p. 1727 - 1730 (2008/02/02)
A series of β-carboxamido-phosphon(in)ic acids (2) was identified as a new structural motif for obtaining potent inhibitors of human mast cell chymase. For example, 1-naphthyl derivative 5f had an IC50 value of 29 nM and (E)-styryl derivative 6
The Preparation and Oxidative Dimerisation of 2-Acetyl-7-hydroxy-1,2,3,4-tetrahydroisoquinoline. A New Approach to Tetrahydroisoquinoline Synthesis
Ajao, J. F.,Bird, C. W.
, p. 329 - 331 (2007/10/02)
The title compound has been prepared from 1,2,3,4-tetrahydroisoquinoline via successive nitration, acetylation, reduction and diazotisation.Earlier conflicting reports on the nitration of tetrahydroisoquinoline have been clarified.A better synthetic route
