1010411-21-8 Usage
Description
GSK369796, also known as 5-[(7-Chloro-4-quinolinyl)amino]-2-[[(1,1-dimethylethyl)amino]methyl]phenol Hydrochloride, is an aminoquinoline antimalarial compound. It is a derivative of the aminoquinoline class of compounds, which are known for their antimalarial properties. GSK369796 has been developed to target and inhibit the growth of Plasmodium parasites, the causative agents of malaria.
Used in Pharmaceutical Industry:
GSK369796 is used as an antimalarial drug for the treatment of malaria caused by Plasmodium parasites. It is effective in inhibiting the growth and replication of the parasites, thereby reducing the severity and duration of the disease. The development of GSK369796 aims to provide a new option for malaria treatment, potentially offering improved efficacy and safety compared to existing antimalarial drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 1010411-21-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,1,0,4,1 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1010411-21:
(9*1)+(8*0)+(7*1)+(6*0)+(5*4)+(4*1)+(3*1)+(2*2)+(1*1)=48
48 % 10 = 8
So 1010411-21-8 is a valid CAS Registry Number.
1010411-21-8Relevant articles and documents
Candidate selection and preclinical evaluation of N-tert-Butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century
, p. 1408 - 1415 (2009)
N-tert-Butyl isoquine (4) (GSK369796) is a 4-aminoquinoline drug candidate selected and developed as part of a public-private partnership between academics at Liverpool, MMV, and GSK pharmaceuticals. This molecule was rationally designed based on chemical
