1010446-86-2Relevant articles and documents
Facile reduction of malonate derivatives using NaBH4/Br2: an efficient route to 1,3-diols
Tudge, Matthew,Mashima, Hiroko,Savarin, Cecile,Humphrey, Guy,Davies, Ian
, p. 1041 - 1044 (2008)
Borane-dimethoxyethane generated from sodium borohydride-bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.