Facile reduction of malonate derivatives using NaBH4/Br2: an efficient route to 1,3-diols

DOI: 10.1016/j.tetlet.2007.12.001

Source and publish data:

Tetrahedron Letters p. 1041 - 1044 (2008)

Update date:2022-08-04

Topics:

Authors:

Tudge, Matthew

Mashima, Hiroko

Savarin, Cecile

Humphrey, Guy

Davies, Ian

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/j.tetlet.2007.12.001

Borane-dimethoxyethane generated from sodium borohydride-bromine mixtures efficiently reduces a wide range of malonate derivatives to the corresponding 1,3-diols. This new reagent system represents a milder alternative to current methods available, providing the requisite 1,3-diols in higher yields over shorter reaction times.

Full text of DOI:10.1016/j.tetlet.2007.12.001

Products guided by the article

Product name:C₁₃H₁₇BrF₂O₂

Cas No:1010446-86-2

R&D Labs maybe for 1010446-86-2

Shanghai AoBo Bio-Pharmaceutical Technology Co., Ltd.

Contact:+86-21-51320130-801, 816

Address:Room 601, No. 1011, Halei Road, Zhangjiang High-Tech Park, Pudong, Shanghai
New Forms

Contact:+31-24-3886056

Address:Binderskampweg 29 Unit 36
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Jinan Hongfangde Pharmatech Co.LTD

Contact:0531-88870908

Address:F Bldg,750#,Shunhua Rd,New&High-tech Zone,Jinan,Shandong,China 250101
ZIBO GREEN TRADE CO., LTD

Contact:0543-3317184

Address:No.1401, Unit 1, Global building, Binzhou city, shandong PRC.

Relevant to this article

Doi:10.1002/hlca.19610440427
(1961)
Synthesis, characterization, and electrochemical and electrical properties of novel pentaerythritol-bridged cofacial bismetallophthalocyanines and their water-soluble derivatives

Doi:10.1002/ejic.200700141
(2007)
Bronsted acid-catalyzed insertion of aryldiazoacetates to sp ² carbon-CHO bond: Facile construction of chiral all-carbon quaternary center

Doi:10.1021/ja710532j
(2008)
Calcitonin gene-related peptide (CGRP) receptor antagonists: Investigations of a pyridinone template

Doi:10.1016/j.bmcl.2007.11.042
(2008)
Ligand-free Ullmann-type C-heteroatom couplings under practical conditions

Doi:10.1002/ejoc.201400033
(2014)
Silanol dyes for solar cells: Higher efficiency and significant durability

Doi:10.1002/aoc.1612
(2010)

Article Doi