1010456-21-9Relevant articles and documents
Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor α agonists
Faucher, Nicolas,Martres, Paul,Laroze, Alain,Pineau, Olivier,Potvain, Florent,Grillot, Didier
, p. 710 - 715 (2008/09/19)
Starting from the structure of 5, a two-step strategy was applied to identify a new generation of trifluoromethane sulfonamides as potent PPARα agonists. Synthesis, in vitro and in vivo evaluation of the most potent compound are reported.