401573-32-8

Upstream product

• 53718-43-7 N-(4-cyanophenyl)-1,1,1-trifluoromethane sulfonamide 
• 401573-22-6 tert-butyl N-[(4-trifluoromethylsulfonylamino)benzyl]carbamate 

Downstream Products

• 1010456-17-3 C₁₉H₁₆F₃N₃O₃S₂ 
• 1010456-23-1 C₁₉H₁₇F₃N₄O₅S 
• 1010456-27-5 C₁₈H₁₅F₃N₂O₄S₂ 
• 1010456-19-5 C₂₁H₁₆ClF₃N₂O₃S 
• 1010456-25-3 C₂₂H₁₈ClF₃N₂O₃S 
• 1010456-21-9 C₂₂H₁₆F₃N₃O₃S 
• 385770-68-3 N-[4-((6R,12aR)-6-benzo[1,3]dioxol-5-yl-1,4-pyrazino[1',2':1,6]pyrido[3,4-b]indol-2-yl-methyl)phenyl]-1,1,1-trifluoromethanesulfonamide 

Relevant academic research and scientific papers

Design, synthesis and evaluation of trifluoromethane sulfonamide derivatives as new potent and selective peroxisome proliferator-activated receptor α agonists

Starting from the structure of 5, a two-step strategy was applied to identify a new generation of trifluoromethane sulfonamides as potent PPARα agonists. Synthesis, in vitro and in vivo evaluation of the most potent compound are reported.

N-4-Substituted-benzyl-N′-tert-butylbenzyl thioureas as vanilloid receptor ligands: Investigation on the role of methanesulfonamido group in antagonistic activity

A series of N-4-substituted-benzyl-N′-tert-butylbenzyl thioureas were prepared for the study of their agonistic/antagonistic activities to the vanilloid receptor in rat DRG neurons. Their structure-activity relationship reveals that not only the two oxyge