101067-50-9

Basic information

• Product Name: 2-phenyl-N-(4'-methoxybenzylidene)ethanolamine
• Synonyms: 2-phenyl-N-(4'-methoxybenzylidene)ethanolamine
• CAS NO: 101067-50-9
• Molecular Weight: 255.316
• Mol File: 101067-50-9.mol

Chemical Properties

• CAS DataBase Reference: 2-phenyl-N-(4'-methoxybenzylidene)ethanolamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-N-(4'-methoxybenzylidene)ethanolamine(101067-50-9)
• EPA Substance Registry System: 2-phenyl-N-(4'-methoxybenzylidene)ethanolamine(101067-50-9)

Safety Data

• Hazardous Substances Data: 101067-50-9(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 7568-93-6 2-Amino-1-phenylethanol 

Downstream Products

• 93681-44-8 2-(4'-methoxyphenyl)-3-phenoxy-5-phenyloxazolidine 
• 93681-48-2 1-(2-Hydroxy-2-phenyl-ethyl)-4-(4-methoxy-phenyl)-3-phenoxy-azetidin-2-one 
• 93681-48-2 cis-4-(4'-methoxyphenyl)-3-phenoxy-1-(2'-phenyl-2'-hydroxyethyl)azetidin-2-one 
• 114497-93-7 cis-4-(4'-methoxyphenyl)-3-phenoxy-1-(2'-phenyl-2'-oxoethyl)azetidin-2-one 
• 50899-71-3 cis-4-(4-methoxyphenyl)-3-phenoxy-azetidin-2-one 
• 98767-91-0 cis-4-(4'-methoxyphenyl)-3-phenoxy-1-(1'-bromo-2'-phenyl-2'-oxoethyl)azetidin-2-one 
• 101067-53-2 4-(p-methoxyphenyl)-3-phenoxyazetidin-2-one 
• 101067-51-0 1-(2-Iodo-2-phenyl-ethyl)-4-(4-methoxy-phenyl)-3-phenoxy-azetidin-2-one 
• 101067-54-3 1-(2-Bromo-2-phenyl-ethyl)-4-(4-methoxy-phenyl)-3-phenoxy-azetidin-2-one 
• 101067-52-1 4-(4-Methoxy-phenyl)-3-phenoxy-1-((E)-styryl)-azetidin-2-one 
• 97958-29-7 cis-4-(4'-methoxyphenyl)-1-(2'-phenyl-2'-hydroxyethyl)-3-phthalimidoilazetidin-2-one 
• 97934-57-1 2-(4'-methoxyphenyl)-3-phthalimidoacetyl-5-phenyloxazolidine 
• 97958-29-7 2-[1-(2-Hydroxy-2-phenyl-ethyl)-2-(4-methoxy-phenyl)-4-oxo-azetidin-3-yl]-isoindole-1,3-dione 
• 101067-65-6 [1-(4-Methoxy-phenyl)-meth-(Z)-ylidene]-(2-phenyl-2-trimethylsilanyloxy-ethyl)-amine 

Relevant articles and documents

Synthesis of β-lactams from acetic acids and imines induced by phenyl dichlorophosphate reagent

The development of a practical method for the preparation of vinylamino-β-lactams from Dane salts and Schiff bases is described. Among the reagents known to produce β-lactams from imines and acetic acids, only phenyl dichlorophosphate and 1-methyl-2-chloropyridinium iodide are suitable for the synthesis of vinylamino-β-lactams. Reaction of acetic acids with ethanolimine derivatives promoted by phenyl dichlorophosphate affords oxazolidines instead of β-lactams. Protection of the hydroxyl group as the trimethylsilyl ether in the starting Schiff bases provides a convenient route to the corresponding β-lactams instead of oxazolidines. Some observations on the scope of the method are made.

A NOVEL SYNTHETIC APPROACH TO N-UNSUBSTITUTED β-LACTAMS

A convenient simple route to N-unsubstituted β-lactams is described.Formation of unusual N-styryl-β-lactams is the key of the method.