1010707-11-5Relevant articles and documents
A new strategy for the synthesis of 1,4-benzodiazepine derivatives based on the tandem N-alkylation-ring opening-cyclization reactions of methyl 1-arylaziridine-2-carboxylates with N-[2-bromomethyl(phenyl)]trifluoroacetamides
Wang, Jin-Yuan,Guo, Xue-Fei,Wang, De-Xiang,Huang, Zhi-Tang,Wang, Mei-Xiang
, p. 1979 - 1982 (2008/09/18)
(Chemical Equation Presented) A new method for the synthesis of novel 1,4-benzodiazepine derivatives has been established from a one-pot reaction of methyl 1-arylaziridine-2-carboxylates with N-[2-bromomethyl(aryl)] trifluoroacetamides. The reaction proce