101078-50-6

Basic information

• Product Name: 5-methoxy-2-(4′-tolyl)benzo[d]thiazole
• Synonyms: 5-methoxy-2-(4′-tolyl)benzo[d]thiazole
• CAS NO: 101078-50-6
• Molecular Weight: 255.34
• Mol File: 101078-50-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 5-methoxy-2-(4′-tolyl)benzo[d]thiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methoxy-2-(4′-tolyl)benzo[d]thiazole(101078-50-6)
• EPA Substance Registry System: 5-methoxy-2-(4′-tolyl)benzo[d]thiazole(101078-50-6)

Safety Data

• Hazardous Substances Data: 101078-50-6(Hazardous Substances Data)

Upstream product

• 2942-13-4 6-methoxy-1,3-benzothiazole 
• 104-84-7 para-methylbenzylamine 
• 14371-84-7 4,4′-dimethoxy-2,2′-dinitro-diphenyl disulfide 
• 104-87-0 4-methyl-benzaldehyde 
• 2942-14-5 5-methoxy-1,3-benzothiazole 
• 10298-80-3 2-chloro-5-methoxynitrobenzene 
• 58755-70-7 1-iodo-4-methoxy-2-nitrobenzene 
• 101078-45-9 N-(3-methoxyphenyl)-4-methyl-benzamide 
• 99-94-5 p-Toluic acid 
• 874-60-2 4-methyl-benzoyl chloride 
• 101078-47-1 4-methyl-3'-methoxythiobenzanilide 

Downstream Products

• 101078-53-9 2-(4-methylphenyl)-5-hydroxybenzothiazole 
• 101078-56-2 2-(4-methylphenyl)-5-acetoxybenzothiazole 
• 101078-69-7 diethyl 4-(5-hydroxybenzo[d]thiazol-2-yl)benzylphosphonate 
• 101078-66-4 Acetic acid 2-[4-(diethoxy-phosphorylmethyl)-phenyl]-benzothiazol-5-yl ester 

Relevant articles and documents

Synthesis of 2-substituted benzothiazoles from 1-iodo-2-nitrobenzenes by a copper-catalyzed one-pot three-component reaction

A novel method was developed for synthesizing 2-substituted 1,3-benzothiazoles through a copper-catalyzed, one-pot, three-component reaction of a 1-iodo-2-nitrobenzene with sodium sulfide and an aldehyde. Georg Thieme Verlag Stuttgart - New York.

2-Arylation/alkylation of benzothiazoles using superparamagneticgraphene oxide-Fe3O4 hybrid material as a heterogeneous catalystwith diisopropyl azodicarboxylate (DIAD) as an oxidant

In this report, we introduced Graphene oxide-iron oxide (GO-Fe3O4) nanocomposites as a heterogeneous catalyst for arylation/alkylation of benzothiazoles with aldehydes and benzylic alcohols in the presence of diisopropyl azodicarboxylate (DIAD) as an oxidant which exclusively produced 2-aryl (alkyl)-1H–benzothizoles in moderate to excellent yields. The absence of precious metals and toxic solvent, easy product isolation, and recyclability of the GO-Fe3O4 with no loss of activity are notable advantages of this method.

Synthesis of 2-aryl benzothiazoles via K2S2O 8-mediated oxidative condensation of benzothiazoles with benzylamines

A novel way to synthesize 2-arylbenzothiazoles is described. Reactions of benzothiazoles with diverse benzylamines in the presence of K2S 2O8 and KOt-Bu in DMSO-H2O afforded the desired 2-arylbenzothiazoles in good yields. It is notable that no transition-metal catalyst is needed in this reaction. Compared with other known methods, this method of synthesizing 2-arylbenzothiazoles can be advantageous in cases where substituted benzothiazoles and benzylamines are readily available. Georg Thieme Verlag Stuttgart. New York.