1010798-64-7

Basic information

• Product Name: 3-oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile
• Synonyms: 3-oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile;Tetrahydro-beta-oxo-2H-pyran-4-propanenitrile;3-(oxan-4-yl)-3-oxopropanenitrile
• CAS NO: 1010798-64-7
• Molecular Formula: C8H11NO2
• Molecular Weight: 153.17844
• Mol File: 1010798-64-7.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 268.0±30.0 °C(Predicted)
• Appearance: /
• Density: 1.104±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 9.20±0.20(Predicted)
• CAS DataBase Reference: 3-oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile(1010798-64-7)
• EPA Substance Registry System: 3-oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile(1010798-64-7)

Safety Data

• Hazardous Substances Data: 1010798-64-7(Hazardous Substances Data)

Usage

General Description

The chemical 3-Oxo-3-(tetrahydro-2H-pyran-4-yl)propanenitrile is a compound with the molecular formula C9H11NO2. It is a nitrile derivative that contains a tetrahydro-2H-pyran-4-yl group and a propanenitrile group. This chemical is used in the synthesis of pharmaceuticals and can also be used as a building block for organic synthesis. It has potential applications in the pharmaceutical and agrochemical industries due to its unique structure and reactivity. Its properties and potential uses make it an interesting compound for further study and development in various chemical and pharmaceutical applications.

Upstream product

• 96835-17-5 ethyl tetrahydro-2H-pyran-4-carboxylate 
• 75-05-8 acetonitrile 
• 5337-03-1 tetrahydro-2H-pyran-4-carboxylic acid 
• 110238-91-0 tetrahydropyran-4-carboxylic acid methyl ester 

Downstream Products

• 1414571-25-7 1-phenyl-3-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-5-amine 

Relevant articles and documents

Nitrogen-containing ring derivative inhibitor as well as preparation method and application thereof

The invention relates to a nitrogen-containing ring derivative inhibitor as well as a preparation method and an application thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method thereof, a pharmaceutical composition containing the compound, and uses of the compound as a P2X3 inhibitor in treatment of P2X3 receptor dysfunction diseases, especially in treatment of neurogenic diseases.

NOVEL PYRAZOLO-PYRROLO-PYRIMIDINE-DIONE DERIVATIVES AS P2X3 INHIBITORS

The present invention covers substituted Pyrazolo-pyrrolo-pyrimidine-dione (PPPD) compounds of general formula (I): in which R1, R2 and R3 are as defined herein, methods of preparing said compounds, pharmaceutical compositions and combinations comprising said compounds and the use of said compounds for manufacturing pharmaceutical compositions for the treatment or prophylaxis of diseases, in particular of neurogenic diseases, as a sole agent or in combination with other active ingredients.

PYRAZOLYL UREA, THIOUREA, GUANIDINE AND CYANOGUANIDINE COMPOUNDS AS TRKA KINASE INHIBITORS

Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which ca